THC Tolerance

The Origin Of Tolerance

You know that the feeling of ‘high’ is achieved by THC triggering your brain to produce a lot of dopamine. Well, your brain’s number one role is to regulate your body chemistry and if THC is causing it to produce too much dopamine, it will try to slow down that production.  Your brain will actually remove some CB1 receptors that the THC is activating to bring production of dopamine back to an acceptable level.

A Reversible Process

This is a completely reversible process as when you take a break from THC for a while (3-12 days based on mice studies) then the body will bring back these CB1 receptors.